Author: Riyadh Hasan Mohammed ali

In the current work, N,N′-bipyridyl (N- sulfonic acid) (N′- silica-n-propyl) propane mesylate/chloride bonded to Fe3O4 coated with bilayer silica ([BPSSPMCFS]) was used as a novel bi-functional inorganic-organic hybrid magnetic nanocatalyst to manufacture 10,11-dihydrochromeno[4,3-b]chromene-6,8(7H,9H)-diones under solvent-free conditions. The methods of feld emission scanning electron microscopy (FE SEM), energy-dispersive X-ray spectroscopy (EDX), elemental mapping, Fourier transform infrared spectroscopy (FT-IR), X-ray difraction (XRD) analyses, thermal gravimetric analysis (TGA), vibrating sample magnetometry (VSM) and Brunauer-Emmett-Teller (BET) were used to identify this nanohybrid. The [BPSSPMCFS] produced the mentioned derivatives with great selectivity without producing side products, and besides this important feature, which has always been one of the main problems on the way to the synthesis of these compounds, it has signifcant advantages such as simple synthesis, the use of green media, large surface area, simple separation and workup, very suitable turnover number (TON) and turnover frequency (TOF) values, great reuse for several consecutive cycles without noticeably changing its catalytic activity, and short reaction time. Moreover, the hot fltration technique was used to examine and confrm the heterogeneous nature of [BPSSPMCFS].

This study aims to estimate a simple, rapid and sensitive method for a trace amount of atropine (ATR) in medicinal compounds. Two approaches were followed to accomplish this aim, i.e., spectrophotometric determination of pure ATR and pharmaceutical preparations using SbI4 2− ion as a new reagent. The procedure involves the implementation of an ion-association complex with this alkaloid. The resulting complex was extracted and detected spectrophotometrically at 492 nm. Appropriate parameters were investigated, including the ion SbI4 2− concentration and the pH value of the complex formation. Using chloroform to extract the complex, taking into consideration extraction time and volume of solvent used. The calibration graph is linear in the ranges of 0.5–5.0 × 10−3 M. Precision, accuracy, detection limit, and RSD %, as well as relative standard deviation (n = 5), were calculated. The test sensitivity was 0.013 μg cm−2. Several interference additives were studied by investigating the effect of equal and duplicate quantities of some common excipients on selectivity, such as starch, glucose, lactose, glycerin, and talc. The molar ratio of the SbI4 2−_ATR was determined. The amount of ATR in the pharmaceutical tablets and eye drop preparation was calculated using Erel at ratios of 2.24 and 2.75%, respectively.

ABSTRACT Sensitive and rapid determination of foodborne pathogenic bacteria is of practical importance for the control and prevention of foodborne illnesses. Nowadays, with the prosperous development of fluorescence assays, fluorescence resonance energy transfer (FRET)-derived diagnostic strategies are extensively employed in quantitative analysis of different pathogenic bacteria in food-related matrices, which displays a rapid, simple, stable, reliable, cost-effective, selective, sensitive, and realtime way. Considering the extensive efforts that have been made in this field so far, we here discuss the up-to-date developments of FRET-based diagnostic approaches for the determination of key foodborne pathogens like Staphylococcus aureus, Escherichia coli, Vibrio parahaemolyticus, Salmonella spp., Campylobacter spp., and Bacillus cereus in complex food-related matrices. Moreover, the principle of this technology, the choosing standards of acceptor-donor pairs, and the fluorescence properties are also profiled. Finally, the current prospects and challenges in this field are also put forward

ABSTRACT The primary objective of this investigation was to synthesize a novel antibacterial nanocomposite consisting of natural gellan gum (GG) hydrogel, MnFe LDH, GO, and Fe3O4 nanoparticle, which was developed to adsorb Indigo carmine (IC). The GG hydrogel/MnFe LDH/GO/Fe3O4 nanocomposite was characterized through different analytical, microscopic, and biological methods. The results of adsorption experiments reveal that 0.004 g of the nanocomposite can remove 98.38 % of IC from a solution with an initial concentration of 100 mg/L, within 1 h at room temperature and under acidic pH conditions. Moreover, the nanocomposite material effectively suppressed the in vitro growth of both E. coli and S. aureus strains, with inhibitory rates of 62.33 % and 53.82 %, respectively. The isotherm data obtained in this investigation were fitted by linear and non-linear forms of Langmuir, Freundlich, and Dubinin-Radushkevich (D-R) isotherms equations. The results of the adsorption kinetics study indicated that the pseudo-second-order model best described the experimental data. The findings of this study suggest that the synthesized nanocomposites hold great potential as effective adsorbents for removing IC and bacteria from aqueous solutions.

We designed and prepared a novel N-heterocycle-based nanocatalyst by a post synthetic method, namely the [Fe3O4@DAA-BTrzPhen–Cu(II)] composite. In this method, bistriazolyl-phenanthroline groups were stepwise synthesized on an Fe3O4 substrate and used as a tetradentate nitrogenous ligand for coordinating to copper ions. The obtained nanocomposite was well characterized using FT-IR, PXRD, TGA, EDAX, ICP-OES, EDX-mapping, SEM, TEM, VSM and BET analyses, which confirm the formation of a thermostable crystalline spherical particle morphology with the particle size in the range of 17 nm to 25 nm and a magnetization value of 42 emu g−1 . Also, the catalytic activity of [Fe3O4@DAA-BTrzPhen– Cu(II)] as a novel and magnetically separable heterogeneous nanocatalyst was evaluated in preparing various tetrasubstituted imidazole derivatives from one-pot four-component condensation of anilines, aldehydes, 1,2-diketones and ammonium acetate, and favorable products were produced with excellent yields. The stability, low Cu leaching, and heterogenous nature of the nanocatalyst were confirmed by hot-filtration and leaching tests. The copper based nanocatalyst could be easily recovered by magnetic field separation and recycled at least 8 times in a row without noticeable loss in its catalytic activit

We designed and prepared a novel N-heterocycle-based nanocatalyst by a post synthetic method, namely the [Fe3O4@DAA-BTrzPhen–Cu(II)] composite. In this method, bistriazolyl-phenanthroline groups were stepwise synthesized on an Fe3O4 substrate and used as a tetradentate nitrogenous ligand for coordinating to copper ions. The obtained nanocomposite was well characterized using FT-IR, PXRD, TGA, EDAX, ICP-OES, EDX-mapping, SEM, TEM, VSM and BET analyses, which confirm the formation of a thermostable crystalline spherical particle morphology with the particle size in the range of 17 nm to 25 nm and a magnetization value of 42 emu g−1 . Also, the catalytic activity of [Fe3O4@DAA-BTrzPhen– Cu(II)] as a novel and magnetically separable heterogeneous nanocatalyst was evaluated in preparing various tetrasubstituted imidazole derivatives from one-pot four-component condensation of anilines, aldehydes, 1,2-diketones and ammonium acetate, and favorable products were produced with excellent yields. The stability, low Cu leaching, and heterogenous nature of the nanocatalyst were confirmed by hot-filtration and leaching tests. The copper based nanocatalyst could be easily recovered by magnetic field separation and recycled at least 8 times in a row without noticeable loss in its catalytic activit