Investigating the Efficiency of Simple Aqueous Extract of Nigella Sativa Activity Against Serratia Marcescens Bactria

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ABSTRACT
Nigella sativa seeds is considered as a very effective treatment for a variety of
human diseases in traditional medicine worldwide with low human toxicity.
Serratia marcescens pathogenic species, a Gram-negative, opportunistic
bacteria, are widespread and distributed in the human environment with
considered resistance to different types of antibiotics. Extraction was performed
on 12.5 gm. /150 ml of Nigella seeds using rotary evaporator. Different time
periods for extraction were applied (1-4 hours) with different temperature ranges
of 50 °C to 60 °C performed separately for each time period. The 3 and 4 hours
extraction period at 60 °C for seeds was effective against Serratia marcescens
with inhibition zone of 11.18 and 12.27 mm respectively. Nigella seeds could be
a promising inhibitor with enhanced activity against Serratia marcescens. Water
extraction was efficient and effective at 60 °C, with extraction period of 2-3
hours for seeds. No activity recorded below this temperature.
KEYWORDS: Nigella Sativa; Serratia marcescens; water Nigella Extract
activity; Treatment of Serratia marcescens with nigella sativa

DOI Link: Investigating the Efficiency of Simple Aqueous Extract of Nigella Sativa Activity Against Serratia Marcescens Bactria