Hussain SA, Hassan MQ, Zeki MA. Antioxidant profile of human erythrocytes after kidney transplantation. Clin Biochem. 1995 Dec;28(6):607-10. doi: 10.1016/0009-9120(95)00033-6. PMID: 8595710.
Several lines of evidence suggest that oxygen free radicals are involved in the toxicity of uremia in dialyzed and undialyzed patients. Elevated levels of erythrocyte, plasma, and platelet malondialdehyde, an indicator of lipid peroxidation, have been observed in patients with chronic uremia. Conjugated diene fatty acids are another index of increased lipid peroxidation, and increases in conjugated diene fatty acids have been reported in the plasma and adipose tissue of chronic renal failure patients. No previous studies have assessed the effects of renal transplantation on biochemical parameters commonly used to characterize antioxidant activity associated with uremia toxicity. Therefore, the pretransplant biochemical profile of human erythrocytes has been compared with the biochemical profile of human erythrocytes 2 weeks following a successful kidney transplant in 6 patients with chronic renal failure.
https://doi.org/10.1016/0009-9120(95)00033-6.
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